Institute for Systems Biology

Institute for Systems Biology

The Institute for Systems Biology is a nonprofit biomedical research organization based in Seattle, Washington. It was founded in 2000 by systems biologist Leroy Hood, immunologist Alan Aderem, and protein chemist Ruedi Aebersold. ISB was established on the belief that the conventional models for exploring and funding breakthrough science have not caught up with the real potential of what is possible today. ISB serves as the ultimate environment where scientific collaboration stretches across disciplines, where our researchers have the intellectual freedom to challenge the status quo, and where grand visions for breakthroughs in human health inspire a collective drive to achieve the seemingly impossible. Our core values ensure that we always keep our focus on the big ideas that eventually will have the biggest impact on human health. Since 2000, ISB has grown to about 200 staffers, which includes 9 faculty members and laboratory groups.

Sanger Institute’s COSMIC database expands cancer cloud capabilities at the Institute for Systems Biology - Institute for Systems Biology

"Having COSMIC data within ISB-GCG (, which is funded by the National Institutes of Health’s National Cancer Institute, enables new types of cloud-based and cloud-powered analyses across a number of resources, including The Cancer Genome Atlas (TCGA).": The Wellcome Trust Sanger Institute released this news on Feb. 20, 2017. See original release… FOR IMMEDIATE RELEASE The Wellcome Trust Sanger Institute’s Catalog of Somatic Mutations in Cancer (COSMIC) team announces a new agreement to provide their... Read More

Introduce One-cell Doubling Evaluation of Living Arrays of Yeast! ODELAY! - Institute for Systems Biology

New study in "G3: Genes, Genomes, Genetics": Scientists at ISB introduce ODELAY, a powerful automated and scalable growth analysis platform that uses time-lapse microscopy to photograph individual yeast cells growing into colonies. 3 Bullets: ISB researchers developed a powerful new growth-analysis tool called ODELAY. ODELAY uses time-lapse microscopy to monitor growth of yeast cells and observe heterogeneity. The ODELAY platform has wide-ranging applications and enables quantitative measurements similar tools don’t... Read Mo...

K12 Engineering Scholars Program

Why it matters to support K-12 teachers in STEM education. Tell your favorite 4-8th grade teacher in Washington State to apply for this summer program.

Why should teachers apply? Learn more at

K12 Engineering Scholars Program Seeks Applicants - Institute for Systems Biology

We are now accepting applications from STEM teachers (grades 4-8) for the K12 Engineering Scholars Program. Share with any teachers you know! The UW College of Engineering and ISB’s Logan Center for Education are excited to announce a second year of the K12 Engineering Scholars Program. The program seeks 4th-8th grade teachers of STEM to apply for a summer program.... Read More

Summer Research Internships - Institute for Systems Biology

2017 ISB Summer internship applications for high school and undergraduate students are now open! ISB offers summer research internships for college undergraduates and high school students. Positions are competitive and the experience is unparalleled.

CRI Awards Grant to Develop Powerful Genomic Data Resource for Cancer Immunotherapy Researchers

Great news from ISB's Shmulevich Lab: CRI iAtlas to provide immune bioinformatics tool that aims to improve cancer immunotherapy research and drug effectiveness.

About ISB

It takes a unique team of researchers who are trained in dozens of scientific disciplines to dive deep into the molecular machines of life so they can analyze intricate levels of details in order to understand what causes our bodies to function - or not function. Our scientists want to better predict, prevent, and reduce the effect of human diseases, and to understand what role the environment might play. Ultimately, we want everyone to enjoy a longer, healthier life.

Nurse's Notes: The promise of systems biology

Need to explain systems biology to your family and friends? ISB Director Dr. Nitin Baliga offers this engaging article in the Missoulian Newspaper that will help. When scientists talk about cutting-edge research, it’s an abstract concept to most people. No subway map lights up to show you how an advancement in the lab connects via other

Videos (show all)

About ISB
ISB Symposium




401 Terry Ave N
Seattle, WA
Other Seattle schools (show all)
Seattle School Seattle School

Puget Sound Community School Puget Sound Community School
660 S Dearborn St
Seattle, 98134

Turning Passion into Achievement.

Pacific Northwest Ballet Pacific Northwest Ballet
301 Mercer St
Seattle, 98109

Pacific Northwest Ballet's official facebook page.

8 Limbs Yoga Centers 8 Limbs Yoga Centers
500 E Pike St
Seattle, 98122

With four Seattle neighborhood studios, 8 Limbs offers over 100 classes a day with exceptional teachers, Teacher Training, Retreats, Series & more.

Language Institute at UPC Language Institute at UPC
4540 15th Ave NE
Seattle, 98105

The LI at UPC serves refugees, immigrants, and foreign students through ESL classes and home tutoring.

Pottery Northwest Pottery Northwest
226 1st Ave N
Seattle, 98109

The mission of Pottery Northwest is to develop and promote excellence in the ceramic arts. Pottery Northwest’s goal is to provide a professional facility in an educational atmosphere for the enhancement of skills in the medium of clay.

Northwest Academy for the Healing Arts Northwest Academy for the Healing Arts
4507 44th Ave SW
Seattle, 98116

The Northwest's finest independent massage school. Campuses in Seattle, Tacoma, and Bellingham, WA

Pratt Fine Arts Center Pratt Fine Arts Center
1902 S Main St
Seattle, 98144

The Place to Make Art

Institute for Corporate Productivity Institute for Corporate Productivity
411 1st Ave S, Ste 403
Seattle, 98104

i4cp discovers the people practices that drive high performance. Learn more at

Seattle Country Day School Seattle Country Day School
2619 4th Avenue N
Seattle, 98109

YMCA Powerful Schools YMCA Powerful Schools
3401 Rainier Ave S, Ste C
Seattle, 98144

The Ballet Studio The Ballet Studio
4556 University Way NE
Seattle, 98105

Ballet Exclusively, Adults Exclusively